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  • HGH - Human Growth Hormone | www.SymboMASS.to

  • Human growth hormone (HGH) is one of the major hormones influencing growth and development in humans. Such is the complexity of human growth, a period extending from birth to the age of 20 years, that a very large number of hormones influence it, producing many complex interactions. Besides HGH, the hormones, testosterone, oestradiol, cortisol, thyroxine and insulin have important roles at different stages of growth and development.

    The most obvious action of HGH is that it stimulates somatic growth in pre-adolescents, but it also has metabolic effects. The importance of these metabolic actions in homeostatic regulation of fuel usage and storage is unclear as is the overall role of HGH in the adult. Receptors for HGH are present on the surface of every cell in the body. Discussion of the actions of HGH is futher complicated by the involvement of the plasma growth factors or somatomedins in the action of HGH. HGH stimulates the release mainly from the liver of two hormonal polypeptides, somatomedin C (or insulin-like growth factor I) and somatomedin A (insulin-like growth factor II).

    In this chapter somatomedin C (insulin-like growth factor I) will be known as IGF-I and somatomedin A (insulin-like growth factor II) as IGF-II. IGF-I is the most important of these IGFs but there is still doubt whether many, if any, of the important metabolic effects of HGH are mediated via IGFs.

    HGH seems to have some effects on muscle growth but the effect of IGF-I is greater. This action appears similar to that of insulin in that it promotes amino acid uptake and stimulates protein synthesis resulting, in children, in an increase in the length and diameter of muscle fibers, while only the latter growth occurs in adults. This stimulation of muscle protein synthesis and growth is qualitatively different to that induced by work, since insulin is required for HGH-stimulated muscle growth but not for that induced by work. However, the action of insulin is more likely to be an anti-catabolic effect on muscle protein rather than a direct stimulatory effect on muscle protein synthesis.

    The actions of HGH on metabolism are complex at both the cellular and organ level and appear to be biphasic. In the first or acute phase, which seems to involve the action of HGH alone, amino acid uptake into muscle and liver is stimulated, and there is increased glucose uptake into muscle and adipose tissue together with reduced fat metabolism. During the second, chronic phase, mediated by the IGFs, there is increased lipolysis in adipose tissue resulting in a rise in the plasma concentration of fatty acids and increased fatty acid utilization, thus sparing glucose.

    It is worth considering the HGH response to exercise in more detail. Within 20 minutes of beginning exercise to 75-90 per cent VO2max, HGH level rise. The intensity of the response depends on age, level of fitness and body composition. The type of exercise undertaken also produces varying HGH responses. Intense exercise produces earlier HGH secretion, endurance exercise produces HGH peaks in mid-term, while intermittent intense exercise is claimed to result in the highest HGH levels.

    The potential risks of HGH therapy in children have been mentioned together with the close monitoring required in paediatric patients. The recommended standard replacement dose of HGH is about 0.6 IU/kg body weight per week. It is widely assumed that athletes who abuse the drug are taking 10 times this dose. Major side-effects include skeletal changes, enlargement of the fingers and toes, growth of the orbit and lengthening of the jaw. The internal organs enlarge and the cardiomegaly which is produced is often one of the causes of death associated with HGH abuse. Although the skeletal muscle increase in size, there are often complaints of muscle weakness. Biochemical changes include impaired glucose regulation, hyperlipidaemia and insulin resistance. At least once report, however, has found that clinical doses of HGH did not produce diabetic symptoms in children with short stature. These changes described above contribute to the prevalence of diabetes in HGH abusers. Arthritis and impotence often occur after chronic HGH abuse.

    Growth hormone (GH), also known as somatotropin (or as human growth hormone also known as hGH or HGH in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. GH is a stress hormone that raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1. A recombinant form of hGH called somatropin is used as a prescription drug to treat childrens growth disorders and adult growth hormone deficiency.

    A human body has natural mechanisms that reduce the effect of cell death. The major way of ensuring continuity of tissues is through the HGH  – Human Growth Hormone. HGH is produced by the somatotropic cells of the anterior pituitary gland. It promotes cellular regeneration, tissue growth and development. It is responsible for the replacement of cells that are lost diurnally. It also helps the immune system in combating infectious agents like bacteria and viruses.

    Growth hormone is itself produced by cells- the somatotrophs. The cells are subject to death, just like any other cell in the body. The actual reason why production of the hormone diminishes in not certain. The painful truth however, is that at 40, you are already deficient of the hormone and by 80, the regenerative capacity of your cells goes down to 90-95%.

    Everybody faces the same fate in regard to the diminishing levels of HGH. You have seen how essential the hormone is in maintaining the youthful appearance and feel. Also gaining muscle and weightloss. You have also seen how it reduces in level with age and the effects thereof. The big question now is; Are those people older than you and who look younger than you any special. Are their pituitary glands an exception.? This questions are not without a basis. A simple answer is that nobody is special and no pituitary gland is exempted. All have the same destiny. But you can create a new destiny with the help of Sciroxx.

    OPTIMIZING hGH THERAPY WITH DIET AND EXERCISE

    The importance of diet and exercise in optimizing growth hormone levels applies to those who elect growth hormone therapies as well as those who do not. Irregular insulin levels and lack of exercise are known to contribute to accelerated symptoms of aging like heart disease, obesity, diabetes. The diet and exercise recommendations for boosting hGH help to control the endogenous factors of disease and aging as well as enhancing the effectiveness of hGH therapies.

    It is no coincidence that studies on the effects of exercise produce many of the same results as studies on growth hormone therapy, including increased bone density and muscle mass, reduction of cholesterol, blood pressure, and triglycerides, decreased body fat, and increased life expectancy. Exercise and dietary control of insulin both work to increase growth hormone secretion. Imagine the accelerated influence of combining proper diet, exercise and GH therapy. Many elderly people have limited strength and stamina that affects their ability to exert themselves to the point of making significant gains against heart disease and osteoporosis. Restoring growth hormone levels often increases their energy, strength and stamina so they are able to do exercises that previously seemed impossible. The proper dietary measures can help to enhance growth hormone release and the effects of IGF-1 so that better results are obtained more quickly.

    The New England Journal of Medicine, in their recent study, has established that HGH causes a dramatic decrease in body fat and an increase in lean body mass.


    Human Growth Hormone is produced by many reputable pharmaceutical companies such as:

    Jintopin 4IU by GenSci China
    Jintopin 10IU by GenSci China
    Hygetropin by Hygene China
    SciTropin by Sciroxx

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